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Pharmacokinetics of E-5-(2-Bromovinyl)-2′-Deoxyuridine in Mice

The pharmacokinetics of the newly developed anti-herpes agent, E-5-(2-bromovinyl)-2′-deoxyuridine, was compared with that of the standard anti-herpes drug 5-iodo-2′-deoxyuridine. Both compounds were administered to mice at 100 mg/kg by either the intraperitoneal, subcutaneous, or oral route. The act...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: de Clercq, E., Descamps, J., de Somer, P., Barr, P. J., Jones, A. S., Walker, R. T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/225987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.2.234
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