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Treatment of experimental herpes simplex virus encephalitis with (E)-5-(2-bromovinyl)-2'-deoxyuridine in mice.

(E)-5-(2-Bromovinyl)-2'-deoxyuridine (BVDU) was examined for its ability to increase the survival rate of mice infected intracerebrally with herpes simplex virus type 1 (strain KOS). BVDU was administered orally (through the drinking water), intraperitoneally, or subcutaneously at doses ranging...

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Bibliographic Details
Main Authors: de Clercq, E, Zhang, Z X, Sim, I S
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC183760/
https://ncbi.nlm.nih.gov/pubmed/7137983
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