Pharmacokinetics of E-5-(2-Bromovinyl)-2′-Deoxyuridine in Mice

The pharmacokinetics of the newly developed anti-herpes agent, E-5-(2-bromovinyl)-2′-deoxyuridine, was compared with that of the standard anti-herpes drug 5-iodo-2′-deoxyuridine. Both compounds were administered to mice at 100 mg/kg by either the intraperitoneal, subcutaneous, or oral route. The act...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	de Clercq, E., Descamps, J., de Somer, P., Barr, P. J., Jones, A. S., Walker, R. T.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1979
Soggetti:	Pharmacology and Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352829/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/225987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.2.234
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