Metabolic fate of (E)-5-(2-bromovinyl)-2'-deoxyuridine in herpes simplex virus- and mock-infected cells.

(E)-5-(2-Bromovinyl)-2'-deoxyuridine is a potent antiherpes compound with far better activity against herpes simplex virus type 1 than type 2. To understand the role of drug metabolism in this differential antiviral activity, we examined the metabolic fate of this drug in virus-infected and moc...

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Bibliographic Details
Main Authors: Ayisi, N K, De Clercq, E, Wall, R A, Hughes, H, Sacks, S L
Format: Artigo
Language:Inglês
Published: 1984
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC180009/
https://ncbi.nlm.nih.gov/pubmed/6097176
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