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Metabolic fate of (E)-5-(2-bromovinyl)-2'-deoxyuridine in herpes simplex virus- and mock-infected cells.

(E)-5-(2-Bromovinyl)-2'-deoxyuridine is a potent antiherpes compound with far better activity against herpes simplex virus type 1 than type 2. To understand the role of drug metabolism in this differential antiviral activity, we examined the metabolic fate of this drug in virus-infected and mock-inf...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Ayisi, N K, De Clercq, E, Wall, R A, Hughes, H, Sacks, S L
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1984
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6097176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.5.762
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