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Dynamics of Plasmodium falciparum enoyl-ACP reductase and implications on drug discovery

Enoyl-acyl carrier protein reductase (ENR) is a crucial enzyme in the type II fatty acid synthesis pathway of many pathogens such as Plasmodium falciparum, the etiological agent of the most severe form of malaria. Because of its essential function of fatty acid double bond reduction and the absence...

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Detalhes bibliográficos
Main Authors: Lindert, Steffen, McCammon, J Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527710/
https://ncbi.nlm.nih.gov/pubmed/22969045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2155
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