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In silico Screening for Plasmodium falciparum Enoyl-ACP Reductase inhibitors

The need for novel therapeutics against Plasmodium falciparum is urgent due to recent emergence of multi-drug resistant malaria parasites. Since fatty acids are essential for both the liver and blood stages of the malarial parasite, targeting fatty acid biosynthesis is a promising strategy for comba...

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Bibliografiske detaljer
Udgivet i:J Comput Aided Mol Des
Main Authors: Lindert, Steffen, Tallorin, Lorillee C., Nguyen, Quynh G., Burkart, Michael D., McCammon, J. Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278936/
https://ncbi.nlm.nih.gov/pubmed/25344312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-014-9806-3
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