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Structural basis for proton conduction and inhibition by the influenza M2 protein

The influenza M2 protein forms an acid-activated and drug-sensitive proton channel in the virus envelope that is important for the virus lifecycle. The functional properties and high-resolution structures of this proton channel have been extensively studied to understand the mechanisms of proton con...

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Detalhes bibliográficos
Main Authors: Hong, Mei, DeGrado, William F
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527700/
https://ncbi.nlm.nih.gov/pubmed/23001990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2158
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