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Structural and Dynamic Mechanisms for the Function and Inhibition of the M2 Proton Channel From Influenza A Virus
The M2 proton channel from influenza A virus, a prototype for a class of viral ion channels known as viroporins, conducts protons along a chain of water molecules and ionizable side chains, including His37. Recent studies highlight a delicate interplay between protein folding, proton binding and pro...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039100/ https://ncbi.nlm.nih.gov/pubmed/21247754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2010.12.002 |
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