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Peripheral Leptin Regulates Bone Formation

Substantial evidence does not support the prevailing view that leptin, acting through a hypothalamic relay, decreases bone accrual by inhibiting bone formation. To clarify the mechanisms underlying regulation of bone architecture by leptin, we evaluated bone growth and turnover in wild type (WT) mic...

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Detalhes bibliográficos
Main Authors: Turner, Russell T., Kalra, Satya P., Wong, Carmen P., Philbrick, Kenneth A., Lindenmaier, Laurence B., Boghossian, Stephane, Iwaniec, Urszula T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527690/
https://ncbi.nlm.nih.gov/pubmed/22887758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1734
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