Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive and psychiatric manifestations. Since the mutation responsible for the disease was identified as an unstable expansion of CAG repeats in the gene encoding the huntingtin protein in 1993, n...

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Main Authors: Menalled, Liliana B., Kudwa, Andrea E., Miller, Sam, Fitzpatrick, Jon, Watson-Johnson, Judy, Keating, Nicole, Ruiz, Melinda, Mushlin, Richard, Alosio, William, McConnell, Kristi, Connor, David, Murphy, Carol, Oakeshott, Steve, Kwan, Mei, Beltran, Jose, Ghavami, Afshin, Brunner, Dani, Park, Larry C., Ramboz, Sylvie, Howland, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527464/
https://ncbi.nlm.nih.gov/pubmed/23284626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049838
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