Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive and psychiatric manifestations. Since the mutation responsible for the disease was identified as an unstable expansion of CAG repeats in the gene encoding the huntingtin protein in 1993, n...

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Autors principals: Menalled, Liliana B., Kudwa, Andrea E., Miller, Sam, Fitzpatrick, Jon, Watson-Johnson, Judy, Keating, Nicole, Ruiz, Melinda, Mushlin, Richard, Alosio, William, McConnell, Kristi, Connor, David, Murphy, Carol, Oakeshott, Steve, Kwan, Mei, Beltran, Jose, Ghavami, Afshin, Brunner, Dani, Park, Larry C., Ramboz, Sylvie, Howland, David
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527464/
https://ncbi.nlm.nih.gov/pubmed/23284626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049838
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