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Total Synthesis of Septocylindrin B and C-Terminus Modified Analogues
The total synthesis is reported of the peptaibol Septocylindrin B which is related to the well documented channel forming peptaibol antibiotic Alamethicin. Several analogues were synthesized with a modified C-terminus, to investigate the SAR of the terminal residue Phaol. All these peptides were tes...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527430/ https://ncbi.nlm.nih.gov/pubmed/23284749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051708 |
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