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Total Synthesis of the Natural Product (±)-Dibromophakellin and Analogues

[Image: see text] (±)-Dibromophakellin has been synthesized in two steps from a known alkene intermediate. The key step in the synthesis is the NBS olefin activation to facilitate the addtion of a guanidine molecule across the double bond.

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Detalles Bibliográficos
Main Authors: Hewlett, Nicole M., Tepe, Jetze J.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162990/
https://ncbi.nlm.nih.gov/pubmed/21797255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol201741r
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