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Natural product scaffolds as inspiration for the design and synthesis of 20S human proteasome inhibitors

The 20S proteasome is a valuable target for the treatment of a number of diseases including cancer, neurodegenerative disease, and parasitic infection. In an effort to discover novel inhibitors of the 20S proteasome, many reseaarchers have looked to natural products as potential leads for drug disco...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:RSC Chem Biol
Päätekijät: Hubbell, Grace E., Tepe, Jetze J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: RSC 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009326/
https://ncbi.nlm.nih.gov/pubmed/33791679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cb00111b
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