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Influence of the Internalization Pathway on the Efficacy of siRNA Delivery by Cationic Fluorescent Nanodiamonds in the Ewing Sarcoma Cell Model

Small interfering RNAs (siRNAs) are powerful tools commonly used for the specific inhibition of gene expression. However, vectorization is required to facilitate cell penetration and to prevent siRNA degradation by nucleases. We have shown that diamond nanocrystals coated with cationic polymer can b...

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Detalhes bibliográficos
Main Authors: Alhaddad, Anna, Durieu, Catherine, Dantelle, Géraldine, Le Cam, Eric, Malvy, Claude, Treussart, François, Bertrand, Jean-Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527409/
https://ncbi.nlm.nih.gov/pubmed/23284935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052207
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