Influence of the Internalization Pathway on the Efficacy of siRNA Delivery by Cationic Fluorescent Nanodiamonds in the Ewing Sarcoma Cell Model

Small interfering RNAs (siRNAs) are powerful tools commonly used for the specific inhibition of gene expression. However, vectorization is required to facilitate cell penetration and to prevent siRNA degradation by nucleases. We have shown that diamond nanocrystals coated with cationic polymer can b...

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Main Authors: Alhaddad, Anna, Durieu, Catherine, Dantelle, Géraldine, Le Cam, Eric, Malvy, Claude, Treussart, François, Bertrand, Jean-Rémi
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527409/
https://ncbi.nlm.nih.gov/pubmed/23284935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052207
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