Phosphonopeptides as Antibacterial Agents: Rationale, Chemistry, and Structure-Activity Relationships

Peptide mimetics with C-terminal residues simulating natural amino acids have been designed as inhibitors of bacterial cell wall biosynthesis. The phosphonopeptide series consisting of various l and d residues of natural amino acids combined with 1-aminoalkyl (and aryl-alkyl-) phosphonic acid residu...

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Bibliografske podrobnosti
Main Authors: Atherton, Frank R., Hali, Michael J., Hassall, Cedric H., Lambert, Robert W., Ringrose, Peter S.
Format: Artigo
Jezik:Inglês
Izdano: 1979
Teme:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC352738/
https://ncbi.nlm.nih.gov/pubmed/525986
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