Phosphonopeptides as Antibacterial Agents: Rationale, Chemistry, and Structure-Activity Relationships

Peptide mimetics with C-terminal residues simulating natural amino acids have been designed as inhibitors of bacterial cell wall biosynthesis. The phosphonopeptide series consisting of various l and d residues of natural amino acids combined with 1-aminoalkyl (and aryl-alkyl-) phosphonic acid residu...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Atherton, Frank R., Hali, Michael J., Hassall, Cedric H., Lambert, Robert W., Ringrose, Peter S.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1979
Fag:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352738/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/525986/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.5.677
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