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Rotenone Inhibits Autophagic Flux Prior to Inducing Cell Death
[Image: see text] Rotenone, which selectively inhibits mitochondrial complex I, induces oxidative stress, α-synuclein accumulation, and dopaminergic neuron death, principal pathological features of Parkinson's disease. The autophagy–lysosome pathway degrades damaged proteins and organelles for...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526971/ https://ncbi.nlm.nih.gov/pubmed/23259041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300145z |
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