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Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent
Glioblastoma (GBM) is a high-grade central nervous system malignancy and despite aggressive treatment strategies, GBM patients have a median survival time of just 1 year. Chloroquine (CQ), an antimalarial lysosomotropic agent, has been identified as a potential adjuvant in the treatment regimen of G...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940627/ https://ncbi.nlm.nih.gov/pubmed/20406898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop048 |
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