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Low-Dose Bafilomycin Attenuates Neuronal Cell Death Associated with Autophagy-Lysosome Pathway Dysfunction

We have shown previously that the plecomacrolide antibiotics bafilomycin A1 and B1 significantly attenuate cerebellar granule neuron death resulting from agents that disrupt lysosome function. To further characterize bafilomycin-mediated cytoprotection, we examined its ability to attenuate the death...

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Detalhes bibliográficos
Main Authors: Pivtoraiko, Violetta N., Harrington, Adam J., Mader, Burton J., Luker, Austin M., Caldwell, Guy A., Caldwell, Kim A., Roth, Kevin A., Shacka, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910188/
https://ncbi.nlm.nih.gov/pubmed/20534000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06838.x
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