Low-Dose Bafilomycin Attenuates Neuronal Cell Death Associated with Autophagy-Lysosome Pathway Dysfunction

We have shown previously that the plecomacrolide antibiotics bafilomycin A1 and B1 significantly attenuate cerebellar granule neuron death resulting from agents that disrupt lysosome function. To further characterize bafilomycin-mediated cytoprotection, we examined its ability to attenuate the death...

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Hauptverfasser: Pivtoraiko, Violetta N., Harrington, Adam J., Mader, Burton J., Luker, Austin M., Caldwell, Guy A., Caldwell, Kim A., Roth, Kevin A., Shacka, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910188/
https://ncbi.nlm.nih.gov/pubmed/20534000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06838.x
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