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Oxidation of the Yeast Mitochondrial Thioredoxin Promotes Cell Death

AIMS: Yeast, like other eukaryotes, contains a complete mitochondrial thioredoxin system comprising a thioredoxin (Trx3) and a thioredoxin reductase (Trr2). Mitochondria are a main source of reactive oxygen species (ROS) in eukaryotic organisms, and this study investigates the role of Trx3 in regula...

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Hlavní autoři: Greetham, Darren, Kritsiligkou, Paraskevi, Watkins, Rachel H., Carter, Zorana, Parkin, Jill, Grant, Chris M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526897/
https://ncbi.nlm.nih.gov/pubmed/22770501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4597
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