Chloroquine Resistance in Malaria: Accessibility of Drug Receptors to Mefloquine

The process of mefloquine accumulation was studied in mouse erythrocytes infected with either Plasmodium berghei CS (chloroquine susceptible) or P. berghei CR (chloroquine resistant). In both cases, mefloquine was accumulated by a saturable process with an apparent dissociation constant of 2.5 × 10(...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Antimicrob Agents Chemother
Prif Awduron:	Fitch, Coy D., Chan, Robert L., Chevli, Rekha
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1979
Pynciau:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/371544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.2.258
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