Chloroquine Resistance in Malaria: Accessibility of Drug Receptors to Mefloquine

The process of mefloquine accumulation was studied in mouse erythrocytes infected with either Plasmodium berghei CS (chloroquine susceptible) or P. berghei CR (chloroquine resistant). In both cases, mefloquine was accumulated by a saturable process with an apparent dissociation constant of 2.5 × 10(...

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Bibliografski detalji

Izdano u:	Antimicrob Agents Chemother
Glavni autori:	Fitch, Coy D., Chan, Robert L., Chevli, Rekha
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1979
Teme:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/371544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.2.258
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