Chloroquine Resistance in Malaria: Accessibility of Drug Receptors to Mefloquine

The process of mefloquine accumulation was studied in mouse erythrocytes infected with either Plasmodium berghei CS (chloroquine susceptible) or P. berghei CR (chloroquine resistant). In both cases, mefloquine was accumulated by a saturable process with an apparent dissociation constant of 2.5 × 10(...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Fitch, Coy D., Chan, Robert L., Chevli, Rekha
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1979
Témata:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/371544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.2.258
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