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Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain
The CD3ε and ζ cytoplasmic domains of the T cell receptor bind to the inner leaflet of the plasma membrane (PM), and a previous nuclear magnetic resonance structure showed that both tyrosines of the CD3ε immunoreceptor tyrosine-based activation motif partition into the bilayer. Electrostatic interac...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526357/ https://ncbi.nlm.nih.gov/pubmed/23166358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120790 |
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