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Compression of next-generation sequencing reads aided by highly efficient de novo assembly

We present Quip, a lossless compression algorithm for next-generation sequencing data in the FASTQ and SAM/BAM formats. In addition to implementing reference-based compression, we have developed, to our knowledge, the first assembly-based compressor, using a novel de novo assembly algorithm. A proba...

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Détails bibliographiques
Auteurs principaux: Jones, Daniel C., Ruzzo, Walter L., Peng, Xinxia, Katze, Michael G.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526293/
https://ncbi.nlm.nih.gov/pubmed/22904078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks754
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