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Optimizing Information in Next-Generation-Sequencing (NGS) Reads for Improving De Novo Genome Assembly

Next-Generation-Sequencing is advantageous because of its much higher data throughput and much lower cost compared with the traditional Sanger method. However, NGS reads are shorter than Sanger reads, making de novo genome assembly very challenging. Because genome assembly is essential for all downs...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Tsunglin, Tsai, Cheng-Hung, Lee, Wen-Bin, Chiang, Jung-Hsien
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726674/
https://ncbi.nlm.nih.gov/pubmed/23922726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069503
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