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Optimizing Information in Next-Generation-Sequencing (NGS) Reads for Improving De Novo Genome Assembly
Next-Generation-Sequencing is advantageous because of its much higher data throughput and much lower cost compared with the traditional Sanger method. However, NGS reads are shorter than Sanger reads, making de novo genome assembly very challenging. Because genome assembly is essential for all downs...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726674/ https://ncbi.nlm.nih.gov/pubmed/23922726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069503 |
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