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The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival
Type 2 diabetes involves insulin resistance and β-cell failure leading to inadequate insulin secretion. An important component of β-cell failure is cell loss by apoptosis. Apoptosis repressor with caspase recruitment domain (ARC) is an inhibitor of apoptosis that is expressed in cardiac and skeletal...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Diabetes Association
2013
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526036/ https://ncbi.nlm.nih.gov/pubmed/22933109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0504 |
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