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Induction of the Apoptosis Inhibitor ARC by Ras in Human Cancers

Inhibition of apoptosis is critical for carcinogenesis. ARC (apoptosis repressor with caspase recruitment domain) is an endogenous inhibitor of apoptosis that antagonizes both intrinsic and extrinsic apoptosis pathways. Although normally expressed in striated myocytes and neurons, ARC is markedly in...

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Hlavní autoři: Wu, Lily, Nam, Young-Jae, Kung, Gloria, Crow, Michael T., Kitsis, Richard N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885202/
https://ncbi.nlm.nih.gov/pubmed/20392691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114892
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