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Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis and chemoresistance
ARC (Apoptosis Repressor with Caspase recruitment domain) inhibits both death receptor- and mitochondrial/ER-mediated pathways of apoptosis. While expressed mainly in terminally differentiated cells, ARC is markedly upregulated in a variety of human cancers, where its potential contributions have no...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245742/ https://ncbi.nlm.nih.gov/pubmed/22037876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2192 |
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