The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth

Multiple endocrine neoplasia type 1 (MEN1) is a genetic disorder characterized by tissue-specific tumors in the endocrine pancreas, parathyroid, and pituitary glands. Although tumor development in these tissues is dependent upon genetic inactivation of the tumor suppressor Men1, loss of both alleles...

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Bibliographic Details
Published in:PLoS One
Main Authors: McKimpson, Wendy M., Yuan, Ziqiang, Zheng, Min, Crabtree, Judy S., Libutti, Steven K., Kitsis, Richard N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692498/
https://ncbi.nlm.nih.gov/pubmed/26709830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145792
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