The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

Type 2 diabetes involves insulin resistance and β-cell failure leading to inadequate insulin secretion. An important component of β-cell failure is cell loss by apoptosis. Apoptosis repressor with caspase recruitment domain (ARC) is an inhibitor of apoptosis that is expressed in cardiac and skeletal...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: McKimpson, Wendy M., Weinberger, Jeremy, Czerski, Lech, Zheng, Min, Crow, Michael T., Pessin, Jeffrey E., Chua, Streamson C., Kitsis, Richard N.
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2013
Sujets:
Islet Studies
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526036/
https://ncbi.nlm.nih.gov/pubmed/22933109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0504
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires