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Genome-Wide Single-Cell Analysis of Recombination Activity and de novo Mutation Rates in Human Sperm
Meiotic recombination and de novo mutation are the two main contributions towards gamete genome diversity, and many questions remain about how an individual human’s genome is edited by these two processes. Here, we describe a high-throughput method for single-cell whole-genome analysis which was use...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525523/ https://ncbi.nlm.nih.gov/pubmed/22817899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.030 |
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