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Whole-genome molecular haplotyping of single cells

Conventional experimental methods of studying the human genome are limited by the inability to independently study the combination of alleles, or haplotype, on each of the homologous copies of the chromosomes. We developed a microfluidic device capable of separating and amplifying homologous copies...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fan, H Christina, Wang, Jianbin, Potanina, Anastasia, Quake, Stephen R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098715/
https://ncbi.nlm.nih.gov/pubmed/21170043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1739
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