Carregant...
Inverse solvent isotope effects demonstrate slow aquo release from HIF-prolyl hydroxylase (PHD2)
Prolyl Hydroxylase Domain 2 (PHD2) is deemed a primary oxygen sensor in humans yet many details of its underlying mechanism are still not fully understood. (Fe(2+)+αKG)PHD2 is 6-coordinate, with a 2His/1Asp facial triad occupying 3 coordination sites, a bidentate α-ketoglutarate occupying two sites...
Guardat en:
| Autors principals: | , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525350/ https://ncbi.nlm.nih.gov/pubmed/22747465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300229y |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|