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Expression and purification of recombinant human tyrosine hydroxylase as a fusion protein in Escherichia coli

Tyrosine hydroxylase is the rate-limiting step in the synthesis of dopamine and is tightly regulated. Previous studies have shown it to be covalently modified and potently inhibited by 3,4-dihydroxyphenylacetaldehyde (DOPAL), an endogenous neurotoxin via dopamine catabolism which is relevant to Park...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Higgins, Colin A., Vermeer, Lydia M., Doorn, Jonathan A., Roman, David L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525113/
https://ncbi.nlm.nih.gov/pubmed/22659380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2012.05.007
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