Bacteria differentially induce degradation of Bcl-x(L), a survival protein, by human platelets

Bacteria can enter the bloodstream in response to infectious insults. Bacteremia elicits several immune and clinical complications, including thrombocytopenia. A primary cause of thrombocytopenia is shortened survival of platelets. We demonstrate that pathogenic bacteria induce apoptotic events in p...

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Autors principals: Kraemer, Bjoern F., Campbell, Robert A., Schwertz, Hansjörg, Franks, Zechariah G., Vieira de Abreu, Adriana, Grundler, Katharina, Kile, Benjamin T., Dhakal, Bijaya K., Rondina, Matthew T., Kahr, Walter H. A., Mulvey, Matthew A., Blaylock, Robert C., Zimmerman, Guy A., Weyrich, Andrew S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Platelets and Thrombopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525025/
https://ncbi.nlm.nih.gov/pubmed/23086749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-420661
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