Bacteria differentially induce degradation of Bcl-x(L), a survival protein, by human platelets

Bacteria can enter the bloodstream in response to infectious insults. Bacteremia elicits several immune and clinical complications, including thrombocytopenia. A primary cause of thrombocytopenia is shortened survival of platelets. We demonstrate that pathogenic bacteria induce apoptotic events in p...

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Autori principali: Kraemer, Bjoern F., Campbell, Robert A., Schwertz, Hansjörg, Franks, Zechariah G., Vieira de Abreu, Adriana, Grundler, Katharina, Kile, Benjamin T., Dhakal, Bijaya K., Rondina, Matthew T., Kahr, Walter H. A., Mulvey, Matthew A., Blaylock, Robert C., Zimmerman, Guy A., Weyrich, Andrew S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
Soggetti:
Platelets and Thrombopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525025/
https://ncbi.nlm.nih.gov/pubmed/23086749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-420661
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