Bacteria differentially induce degradation of Bcl-x(L), a survival protein, by human platelets

Bacteria can enter the bloodstream in response to infectious insults. Bacteremia elicits several immune and clinical complications, including thrombocytopenia. A primary cause of thrombocytopenia is shortened survival of platelets. We demonstrate that pathogenic bacteria induce apoptotic events in p...

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Autores principales: Kraemer, Bjoern F., Campbell, Robert A., Schwertz, Hansjörg, Franks, Zechariah G., Vieira de Abreu, Adriana, Grundler, Katharina, Kile, Benjamin T., Dhakal, Bijaya K., Rondina, Matthew T., Kahr, Walter H. A., Mulvey, Matthew A., Blaylock, Robert C., Zimmerman, Guy A., Weyrich, Andrew S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525025/
https://ncbi.nlm.nih.gov/pubmed/23086749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-420661
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