Bacteria differentially induce degradation of Bcl-x(L), a survival protein, by human platelets

Bacteria can enter the bloodstream in response to infectious insults. Bacteremia elicits several immune and clinical complications, including thrombocytopenia. A primary cause of thrombocytopenia is shortened survival of platelets. We demonstrate that pathogenic bacteria induce apoptotic events in p...

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主要な著者: Kraemer, Bjoern F., Campbell, Robert A., Schwertz, Hansjörg, Franks, Zechariah G., Vieira de Abreu, Adriana, Grundler, Katharina, Kile, Benjamin T., Dhakal, Bijaya K., Rondina, Matthew T., Kahr, Walter H. A., Mulvey, Matthew A., Blaylock, Robert C., Zimmerman, Guy A., Weyrich, Andrew S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2012
主題:
Platelets and Thrombopoiesis
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525025/
https://ncbi.nlm.nih.gov/pubmed/23086749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-420661
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