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Syntheses of Siderophore–Drug Conjugates Using a Convergent Thiol–Maleimide System

[Image: see text] Three siderophore–drug conjugates (sideromycins) were synthesized by preparation of a maleimide linked derivative of the siderophore desferrioxamine B and reacting the corresponding Ga(3+)-complex with freshly prepared thiol-containing antibiotics: loracarbef, ciprofloxacin, and na...

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Bibliografske podrobnosti
Main Authors: Juárez-Hernández, Raúl E., Miller, Patricia A., Miller, Marvin J.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2012
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524980/
https://ncbi.nlm.nih.gov/pubmed/23264853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300150y
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