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Syntheses of Siderophore–Drug Conjugates Using a Convergent Thiol–Maleimide System
[Image: see text] Three siderophore–drug conjugates (sideromycins) were synthesized by preparation of a maleimide linked derivative of the siderophore desferrioxamine B and reacting the corresponding Ga(3+)-complex with freshly prepared thiol-containing antibiotics: loracarbef, ciprofloxacin, and na...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524980/ https://ncbi.nlm.nih.gov/pubmed/23264853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300150y |
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