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Pyrrole-Imidazole Polyamide Targeting Transforming Growth Factor β1 Ameliorates Encapsulating Peritoneal Sclerosis

♦ Objective: Encapsulating peritoneal sclerosis (EPS) is a devastating fibrotic complication in patients treated with peritoneal dialysis (PD). Transforming growth factor β1 (TGF-β1) is a pivotal factor in the induction of EPS. ♦ Methods: To develop pyrrole-imidazole (PI) polyamide, a novel gene sil...

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Bibliographic Details
Main Authors: Serie, Kazuo, Fukuda, Noboru, Nakai, Shigeki, Matsuda, Hiroyuki, Maruyama, Takashi, Murayama, Yoshinobu, Omata, Sadao
Format: Artigo
Language:Inglês
Published: Multimed Inc 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524855/
https://ncbi.nlm.nih.gov/pubmed/22215658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3747/pdi.2011.00092
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