Quantitation of Pyrrole-Imidazole Polyamide in Rat Plasma by High-Performance Liquid Chromatography Coupled with UV Detection

A simple and robust method using high-performance liquid chromatography with UV detection was developed and validated for the determination of six pyrrole-imidazole (PI) polyamides (HN.49, TGF-β1f, TGF-β1t, HN.50f, HN.50t, and LOX-1) in rat plasma. After the plasma proteins were precipitated with me...

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Detalhes bibliográficos
Main Authors: Kamei, Tomonori, Aoyama, Takahiko, Tanaka, Chihiro, Nagashima, Takafumi, Aoyama, Yukio, Hayashi, Hiroyuki, Nagase, Hiroki, Ueno, Takahiro, Fukuda, Noboru, Matsumoto, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385462/
https://ncbi.nlm.nih.gov/pubmed/22778554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/715928
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