Quantitation of Pyrrole-Imidazole Polyamide in Rat Plasma by High-Performance Liquid Chromatography Coupled with UV Detection

A simple and robust method using high-performance liquid chromatography with UV detection was developed and validated for the determination of six pyrrole-imidazole (PI) polyamides (HN.49, TGF-β1f, TGF-β1t, HN.50f, HN.50t, and LOX-1) in rat plasma. After the plasma proteins were precipitated with me...

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Détails bibliographiques
Auteurs principaux: Kamei, Tomonori, Aoyama, Takahiko, Tanaka, Chihiro, Nagashima, Takafumi, Aoyama, Yukio, Hayashi, Hiroyuki, Nagase, Hiroki, Ueno, Takahiro, Fukuda, Noboru, Matsumoto, Yoshiaki
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385462/
https://ncbi.nlm.nih.gov/pubmed/22778554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/715928
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