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Population structuring of multi-copy, antigen-encoding genes in Plasmodium falciparum

The coexistence of multiple independently circulating strains in pathogen populations that undergo sexual recombination is a central question of epidemiology with profound implications for control. An agent-based model is developed that extends earlier ‘strain theory’ by addressing the var gene fami...

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Detalhes bibliográficos
Main Authors: Artzy-Randrup, Yael, Rorick, Mary M, Day, Karen, Chen, Donald, Dobson, Andrew P, Pascual, Mercedes
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524794/
https://ncbi.nlm.nih.gov/pubmed/23251784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00093
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