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Networks of genetic similarity reveal non-neutral processes shape strain structure in Plasmodium falciparum

Pathogens compete for hosts through patterns of cross-protection conferred by immune responses to antigens. In Plasmodium falciparum malaria, the var multigene family encoding for the major blood-stage antigen PfEMP1 has evolved enormous genetic diversity through ectopic recombination and mutation....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: He, Qixin, Pilosof, Shai, Tiedje, Kathryn E., Ruybal-Pesántez, Shazia, Artzy-Randrup, Yael, Baskerville, Edward B., Day, Karen P., Pascual, Mercedes
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940794/
https://ncbi.nlm.nih.gov/pubmed/29739937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04219-3
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