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Identifying functional groups among the diverse, recombining antigenic var genes of the malaria parasite Plasmodium falciparum from a local community in Ghana

A challenge in studying diverse multi-copy gene families is deciphering distinct functional types within immense sequence variation. Functional changes can in some cases be tracked through the evolutionary history of a gene family; however phylogenetic approaches are not possible in cases where gene...

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Publicat a:PLoS Comput Biol
Autors principals: Rorick, Mary M., Baskerville, Edward B., Rask, Thomas S., Day, Karen P., Pascual, Mercedes
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016947/
https://ncbi.nlm.nih.gov/pubmed/29897905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006174
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