Homology blocks of Plasmodium falciparum var genes and clinically distinct forms of severe malaria in a local population

BACKGROUND: The primary target of the human immune response to the malaria parasite Plasmodium falciparum, P. falciparum erythrocyte membrane protein 1 (PfEMP1), is encoded by the members of the hyper-diverse var gene family. The parasite exhibits antigenic variation via mutually exclusive expressio...

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Hauptverfasser: Rorick, Mary M, Rask, Thomas S, Baskerville, Edward B, Day, Karen P, Pascual, Mercedes
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827005/
https://ncbi.nlm.nih.gov/pubmed/24192078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-13-244
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