Effects of Orexin Gene Transfer in the Dorsolateral Pons in Orexin Knockout Mice

STUDY OBJECTIVES: Narcolepsy is a sleep disorder characterized by loss of orexin neurons. Previously, our group demonstrated that transfer of the orexin gene into surrogate neurons in the lateral hypothalamus and the zona incerta significantly reduced cataplexy bouts in the orexin-ataxin-3 mice mode...

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Bibliographic Details
Main Authors: Blanco-Centurion, Carlos, Liu, Meng, Konadhode, RodaRani, Pelluru, Dheeraj, Shiromani, Priyattam J.
Format: Artigo
Language:Inglês
Published: Associated Professional Sleep Societies, LLC 2013
Subjects:
Effects of Orexin Gene Transfer in Orexin Knockout Mice
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524540/
https://ncbi.nlm.nih.gov/pubmed/23288969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.2296
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