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Effects of Orexin Gene Transfer in the Dorsolateral Pons in Orexin Knockout Mice

STUDY OBJECTIVES: Narcolepsy is a sleep disorder characterized by loss of orexin neurons. Previously, our group demonstrated that transfer of the orexin gene into surrogate neurons in the lateral hypothalamus and the zona incerta significantly reduced cataplexy bouts in the orexin-ataxin-3 mice mode...

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Bibliografske podrobnosti
Main Authors: Blanco-Centurion, Carlos, Liu, Meng, Konadhode, RodaRani, Pelluru, Dheeraj, Shiromani, Priyattam J.
Format: Artigo
Jezik:Inglês
Izdano: Associated Professional Sleep Societies, LLC 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524540/
https://ncbi.nlm.nih.gov/pubmed/23288969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.2296
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