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Orexin gene transfer into the amygdala suppresses both spontaneous and emotion-induced cataplexy in orexin knockout mice

Narcolepsy is a chronic sleep disorder linked to the loss of orexin-producing neurons in the hypothalamus. Cataplexy, a sudden loss of muscle tone during waking, is an important distinguishing symptom of narcolepsy and it is often triggered by strong emotions. The neural circuit underlying cataplexy...

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Détails bibliographiques
Publié dans:Eur J Neurosci
Auteurs principaux: Liu, Meng, Blanco-Centurion, Carlos, Konadhode, Roda Rani, Luan, Liju, Shiromani, Priyattam J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783302/
https://ncbi.nlm.nih.gov/pubmed/26741960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13158
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